Edge's Mewtwo

Edge's Mewtwo (Japanese: えっじミュウツー Etsuji's Mewtwo) is the seventh Pokémon that Edge captured after embarking on his journey, and his eighth overall.

Kanto
Mewtwo made its first appearance when Edge spots its still-unfinished body floating inside a tank while he was infiltrated at the in. Millicas overhears scientist  talking about how there was not enough genetic material in 's cell to complete the body. Later, Mewtwo is eventually finished, but it turns on its creators and escapes.

Mewtwo then proceeded to go on a rampage in, where it would be nicknamed the "Monster of Cerulean City." Edge decided to pursue Mewtwo after learning of its powers and found it inside the. Upon entering, Mewtwo attacks Edge with a tornado made of psychic energy. Edge is saved by Blaine, who reveals that he was a member of Team Rocket and created Mewtwo. Blaine reveals that because he did not have enough of Mew's cells, he was forced to use his own cells to finish Mewtwo's body. However, a few of Mewtwo's cells found their way into his own arm, which gave the two the ability to sense one another. Despite this ability, Blaine stated that he would eventually die from Mewtwo's cells taking over his body.

Blaine attempts to sacrifice himself by charging straight at Mewtwo in an attempt to kill it, but they both survive the attack. Angered from the attack, Mewtwo begins going on the offensive, forcing Edge to try and defend himself. The battle ends when Edge sends Pikachu hurtling down Mewtwo's twister with a  inside his mouth. With Mewtwo captured, Blaine notices that the pain in his arm subsided, which meant that Mewtwo was willing to start over with its creator.

Edge then decides to give Mewtwo to Blaine, since Mewtwo desired to remain with its creator, and Blaine was the rightful owner of the Master Ball. Blaine thanks Edge and promises to keep Mewtwo safe and tells him that he would teach it that humans and Pokémon had more in common than it thought.

Personality and Characteristics
When it first appeared, Mewtwo was very violent and dangerous to approach, often going on rampages, earning it the nickname the "Monster of Cerulean City". After being captured by, Mewtwo calmed down, willing to start over with its Trainer. The Genetic Pokémon also questions its existence in the world and was grateful to discover that it was made from 's eyelash, having something to chase its roots back to.

Mewtwo is a powerful battler, being able make Edge's entire Pokémon team to remain at unease just by its presence. Mewtwo was also capable of completely overwhelming Edge's Aerodactyl and 's effortlessly, and it was only captured after its  twister strategy backfired against it.